Preimplantation Genetic Screening & Diagnosis

Preimplantation Genetic Screening (PGS) and Preimplantation Genetic Diagnosis (PGD) are advanced genetic tests used during IVF to ensure healthy embryos are selected for transfer. These tests help detect genetic abnormalities in embryos before implantation, improving the chances of a successful pregnancy.

What Is Preimplantation Genetic Screening (PGS)?

PGS is a preventive test used to screen embryos for chromosomal abnormalities, such as Down syndrome (Trisomy 21) and chromosomal translocations. It is recommended for couples with no known genetic issues, especially if the female partner is 38 or older, has a history of miscarriage, or has experienced failed IVF attempts.

What Is Preimplantation Genetic Diagnosis (PGD)?

Preimplantation genetic testing is a specialized technique used with in vitro fertilization(IVF). It was used to screen embryos for genetic conditions. They were transferred to the uterus. (PGT)'s main goal was to identify certain genetic disorders or chromosomal abnormalities. In the IVF process, eggs were fertilized with sperm in the laboratory, and embryos were developed for a few days. At the blastocyst stage, day 5 cells are carefully biopsied from the other embryo without disturbing or harming its potential to grow. This genetic analysis was undergone to detect chromosomal abnormalities. Preimplantation genetic diagnosis in India doctors aim to improve implantation without any risk and in a safe method.

Our Procedure for Preimplantation Genetic Screening & Diagnosis Will Include:

• Ovarian stimulation and egg retrieval: women undergo ovarian stimulation with the help of hormone injections. It produces multiple mature eggs.
  
• Fertilization: Retrieved eggs are fertilized with sperm in a lab using IVF and ICSI, their single sperm injected directly into an egg.
  
• Embryo culture: Those fertilized eggs were developed into embryos fertilized in a lab for 3-5 days until they reached the blastocyst.
  
• Embryo biopsy: The biopsy does not harm the embryo's inner cell; typically 5-10 cells are carefully removed from the outer layer of the blastocyst.
  
• Genetic analysis: cells are sent for genetic tests. To identify genetic mutations or chromosomal abnormalities.
  
• Selection and transfer: after the genetic results, one or more healthy embryos are transferred into a woman's uterus for the purpose of implantation. These are the procedures done for preimplantation genetic testing.
  

The process of preimplantation genetic testing is to identify genetic disorders or chromosomal abnormalities. This specialized technique was undergone through IVF (in vitro fertilization). In the IVF process, eggs were fertilized with sperm in the laboratory by the lab experts, and embryos were developed for a few days. At the blastocyst stage, day 5 cells are carefully biopsied from the other embryo without disturbing or harming its potential to grow. This genetic analysis was undergone to detect chromosomal abnormality. Preimplantation genetic testing was one of the most important tests in the process of in vitro fertilization. This process can only be done through the Best IVF center in India. Dr. Aravind Fertility Centre has a 75% high success rate at IVF.

FAQs

1. What is Preimplantation Genetic Screening (PGS)?

    PGS is a test that screens embryos for chromosomal abnormalities before IVF implantation.

2. What is Preimplantation Genetic Diagnosis (PGD)?

    PGD is a test used to identify specific genetic disorders in embryos before IVF implantation.

3. Who should consider PGS?

    PGS is ideal for couples with no known genetic disorders but wanting to screen for chromosomal issues.

4. Who should consider PGD?

    PGD is recommended for couples with known genetic conditions or a family history of genetic disorders.

5. How does PGS help in IVF?

    PGS helps select embryos without chromosomal abnormalities, increasing IVF success rates.

6. How does PGD improve IVF outcomes?

    PGD helps ensure only embryos free of specific genetic disorders are transferred, improving chances of a healthy pregnancy.

7. How is PGD different from PGS?

    PGD screens for specific genetic conditions, while PGS screens for chromosomal abnormalities.