Preimplantation Genetic Screening & Diagnosis
Preimplantation Genetic Screening (PGS) and Preimplantation Genetic Diagnosis (PGD) are advanced genetic tests used during IVF to ensure healthy embryos are selected for transfer. These tests help detect genetic abnormalities in embryos before implantation, improving the chances of a successful pregnancy.
What Is Preimplantation Genetic Screening (PGS)?
PGS is a preventive test used to screen embryos for chromosomal abnormalities, such as Down syndrome (Trisomy 21) and chromosomal translocations. It is recommended for couples with no known genetic issues, especially if the female partner is 38 or older, has a history of miscarriage, or has experienced failed IVF attempts.
What Is Preimplantation Genetic Diagnosis (PGD)?
PGD is used to test embryos for specific genetic disorders that are known to run in the family. It is recommended for couples who are carriers of genetic diseases like cystic fibrosis, sickle cell anemia, or have a family history of chromosome-related issues like Down syndrome.
1. What is Preimplantation Genetic Screening (PGS)?
PGS is a test that screens embryos for chromosomal abnormalities before IVF implantation.
2. What is Preimplantation Genetic Diagnosis (PGD)?
PGD is a test used to identify specific genetic disorders in embryos before IVF implantation.
3. Who should consider PGS?
PGS is ideal for couples with no known genetic disorders but wanting to screen for chromosomal issues.
4. Who should consider PGD?
PGD is recommended for couples with known genetic conditions or a family history of genetic disorders.
5. How does PGS help in IVF?
PGS helps select embryos without chromosomal abnormalities, increasing IVF success rates.
6. How does PGD improve IVF outcomes?
PGD helps ensure only embryos free of specific genetic disorders are transferred, improving chances of a healthy pregnancy.
7. How is PGD different from PGS?
PGD screens for specific genetic conditions, while PGS screens for chromosomal abnormalities.